Installing September CU in SP 2010 Causes Site to Load Slowly

I installed Microsoft's September CU (KB 3115473) in my SP 2010 Dev and Disaster Recovery Farms. All were successful and no errors.

The only issue I have is that after the installation, whenever I open the root site in my DR environment, it takes a little over a minute for the page to load.

I tested in my Dev environment the same thing and it's intermittent. There's times when it takes a minute and sometimes it takes a few seconds.

However, in my DR environment I can say that it takes about a minute or so consistently.

Is there something wrong under the hood? What can I check to see the cause?

I know this can be a pain because there were no errors during installation nor errors on the page. It just takes a little longer than what I'm comfortable with.